Siberian scientists: aggression leads to changes in the structure of the brain and psychosis

In males of mice in a long state of aggression, there is an increase in new neurons in the hippocampus, where stem cells are located. Moreover, in another part of the brain - tonsil - there is a decrease in neuronal activity. In addition, constant skirmishes between animals lead to psychosis

The results of a study carried out at the Federal Research Center Institute of Cytology and Genetics of the SB RAS (Novosibirsk) and in Cold Spring Harbor Laboratory (USA), published in the scientific publication Frontiers in Neuroscience

Writes

"Science in Siberia."

The work used a model of chronic social conflict, which allows you to investigate changes in the brain of mouse males that arise under the influence of the long experience of aggression, accompanied by victories in daily confrontations.

Scientists have established that the rodents have a social behavior and psycho -emotional state, neurological symptoms appear that are preserved for a long time after the cessation of aggressive interactions.

“The growth of new neurons and a change in neuronal activity in the structures of the brain, which was found in joint work with American researchers, reflects the depth of failure in the work of the main mental organ under the influence of re -experience of aggression,” comments Professor Natalia Kudryavtseva, the author of the experimental model and the head of these studies at the Institute of the SB RAS.