
Paolo McKianini became famous in 2011, when he conducted the first operation to transplant an artificial trachea. At that time, he was a professor at the Caroline Institute in Stockholm (representatives of this educational institution determine the Nobel Prize in the field of medicine). McKianini bioenger trache - a plastic tube sown with stem cells of the patient himself - was supposed as an alternative to the donor organs; Theoretically, she could help save hundreds of thousands of lives. In addition, he transplanted trachea from dead people; Their own cells were killed and replaced by stem. According to the scientist, stem cells had to multiply and turn into trachea cells. McKiarini did not test this method on animals; Moreover, his methodology was called revolutionary.
After the transplantation of the artificial trachea, seven of nine of its patients died, the rest of the organ managed to replace with Donorsky. In 2016, the commission, led by the chairman of the Swedish Council for Medical Ethics, found that the scientific justification of operations was insufficient - McKianini's articles on transplantology contained tapped facts. Also, all the risks from such medical intervention were not taken into account. The scientist was fired, and the Swedish government dismissed the rule of the Caroline Institute; Two members of the Nobel Assembly of Stockholm, professors of the Caroline Institute, had to resign. The Swedish prosecutor’s office is still an investigation into the circumstances of McKianini’s operations, the surgeon may be charged with unconducting murder.
McKiarini conducted his operations in Russia. In 2011, he received a grant from the Government of the Russian Federation - about 150 million rubles - and founded a regenerative medicine laboratory on the basis of the Kuban State Medical University. In 2014, the scientist received another grant, this time from the Russian Scientific Fund . In Krasnodar, he conducted four transplantation operations of the bioenginee trachea. The plot of the successful completion of one of them was shown by the first channel, but a year later the plastic tube of the implanted trachea collapsed; After that, the patient died. In the western specialized media, McCaarini was called "Chernobyl Swedish medicine."
In July 2016, Paolo McKianini began working at Kazan Federal University. Then the laboratory “Bioenginery and regenerative medicine” appeared at the university, the leader of which was the scientist. McKiarini oversaw the scientific works of KFU graduate students and continued medical research - he conducted experiments on the monkeys of testing of skffolds (substrates for growing tissues and organs, which can then be transplanted).
The rector of KFU Ilshat Gafurov said that McKiarini chose their university to continue his scientific activity, since equipment at the university is “one of the best in Russia”. McKiarini himself refused to comment and interviews Medusa. In December 2016, the university’s press service published a detailed statement on the university’s website under the heading “Specials and Facts”, which explained why McKianini’s work is important for KFU and medicine as a whole.
On March 21, 2017, Nature Communication magazine recalled the scientific article by Paolo McKayarini about successful transplantation to laboratory rats of the donor trachea-the article was published there in April 2014, after the professor conducted surgery in public. In April 2017, the medical journalist Alla Astakhova, who had previously wrote about McKayarini, reported on her website that the Russian Scientific Fund was not extended by Grant McKianini. This means that the scientist’s project “Creation of tissue engineering design of the esophagus for replacing the damaged organ with a lower prima model”, which he was engaged in KFU, lost financing. The Russian Scientific Fund “Medusa” refused to comment on Grant's review, asking to send a written request.
The rector of KFU Ilshat Gafurov confirmed Medusa that McKianini was leaving the university. “He [McKianini] worked on a grant for us. The grant ends. And he failed to extend it to date, ”Gafurov said. The press service of the university also stated that the scientist “ended with a grant”; To comment on how effective the cooperation of KFU with McKiarini was when exactly the scientist would leave the university and what he would do next, the university representative refused. McKiarini did not respond to the email of the Medusa correspondent.
Sasha Sulim