
Constant anxiety may be one of the first signs of Alzheimer's disease. In addition, if protein plaques appear in the brain cells, then a person’s mood worsens sharply, and this leads him to depression. The study is published in the journal American Journal of Psychiatry. The details of the work are retold by Sciencealert.
Nancy Donovan from Harvard University, together with colleagues, watched 300 volunteers aged 60 to 90 years. Before starting the study, all participants were in their right mind and no one revealed signs of Alzheimer's disease.
The purpose of the doctors was to understand how exactly Alzheimer's disease during development affects the human psyche. Five -year observations of a group of patients showed that all experimental ones had one common feature - anxiety.
When the doctors discovered the participants of the experiment of the plaques of the beta amyloid in the center of the memory, they noted a sharp deterioration in the well-being of patients. People fell into depression, which caused constant anxiety. With the growth of the number of plaques in neurons, concern of patients increased,
According to Donovan, anxiety helps to identify changes in the composition of the neurons of the brain and begin the fight against protein plaques. “Depression and constant anxiety are the first symptoms of Alzheimer's disease that occur even before the cognitive abilities of its carrier begin to deteriorate. If this is confirmed by subsequent studies, then the discovery will help in the early diagnosis and treatment of this disease, ”Donovan is sure.
In recent years, scientists have concluded that Alzheimer's disease causes the accumulation of pathogenic proteins of beta-amyloids in the neurons of the brain. They are formed from another protein that helps to repair damaged neurons and form connections between them.