In Russia, due to the spread of the Delta coronavirus strain, a new surge of the incidence of Covid-19 began. Almost every day, the Federal Operational Headquarters reports on new maximums of daily incidence and mortality. However, the vaccination rate remains low.
Alexander Panchin, candidate of biological sciences, senior researcher at the IPPI RAS molecular evolution sector, member of the RAS Commission for Combating the False Academy, Laureate of the Enlightener Award for the book “The Summary of Biotechnology”, wrote the analysis of the main arguments against Covid vaccination. With the permission of the author, we give its text completely.
Author: Sophi Miyoko Gullbrants I am sure: each of us came across people who believe that the vaccines from coronavirus are evil, a conspiracy and an attempt to turn us into mutants. Recently, I asked subscribers to share exactly what arguments they heard from opponents of vaccinations. After reading hundreds of comments, I highlighted the TOP-20 of the most popular statements that I will try to make out now.
1. "Coronavirus does not exist, no one allocated the virus!"
Biological viruses are a genetic material in the membrane transmitted from cell to cage. Coronavirus SARS-COV-2 has a unique set of genes that is read, published and lies in the public domain. It is impossible to confuse his genes with the genes of some other virus. In laboratories around the world, scientists analyze the genetic sequences of infected viruses. To date, in the international GISAID database there are 4,887,310 readers (aggregates of genes) of the SARS-COV-2 coronavirus. Each such reading confirms the existence of the virus in a particular patient without the slightest doubt. There is no so much genetic data for a single virus.
2. "The scale of the pandemia is exaggerated"
According to WorldMeters, to date, more than 5 048 560 deaths are registered as a result of the COVID-19 (although in reality the figure can be larger). Let's compare the Covid-19 with tuberculosis and HIV, for example. Every year, tuberculosis takes 1.4 million lives, HIV-0.5-1 million lives. Will you still argue that "the danger of coronavirus is exaggerated"?
3. "Covid-19-ordinary SARS. We had previously hurt coronaviruses "
We really had coronaviruses before. But coronaviruses are a large group of viruses, which includes harmless and very dangerous representatives. For example, every tenth person, infected with the atypical pneumonia virus, and every third, infected with the virus of the Middle Eastern respiratory syndrome, die. These are also coronaviruses.
SARS-COV-2 is not so fatal, but much more controversial. In addition, SARS-COV-2 infected with coronavirus has 20 times more chances to die than infected with flu. And the symptomatic course of the Covid-19 often ends with severe and prolonged post-shaped syndrome. At the same time, the virus mutates - and so far in the process of evolution it has become only more dangerous.
4. "Among doctors there is no consensus regarding vaccinations"
Yes, some doctors do not advise vaccinating from Covid-19. What is this talking about? The fact that with medical education in our country everything is not very good. Just keep in mind: if the doctor dissuades you from vaccination, then you need to urgently leave him, and it is better to run away. A good doctor who adheres to the principles of evidence -based medicine never opens against vaccines that have undergone clinical studies.
By the way, recently in Chelyabinsk, the head physician of homeopathic clinic died in Chelyabinsk. He actively opposed vaccination from coronavirus. Guess on one attempt, what did the homeopath die of?
Alexander Panchin 5. "Vaccine can cause coronavirus infection"
There are several coronavirus vaccines in Russia, but I advise you to choose only a “satellite V”. It does not contain coronavirus. Coronavirus SARS-COV-2 has almost three dozen genes. The vaccine contains only one - the genuine S -protein gene. This gene is chosen because it is on the surface of the virus, therefore it is a target for the immune system. To create a vaccine, the physical presence of an original virus in the laboratory is not required. That is, it is impossible to become infected with coronavirus from the vaccine in principle.
6. "Vaccinated contagious"
As already mentioned, the vaccination itself does not cause an infection. But no vaccine guarantees that a person will not get sick. Vaccination reduces the chance to get sick and especially reduces the likelihood of a severe course of the disease and death. Having become infected, a vaccinated person will not weave for so long, will distinguish less than the virus and infect fewer people. It is also important to consider the fact that the probability of getting an infection and the severity of the disease depends on the amount of the virus that a person will receive when contacting the patient.
Nevertheless, vaccinated can be contagious, so they should also observe security measures - in particular, wear masks in places of accumulation of people.
7. "If vaccinated can be sick, then vaccines are not related to attempts to stop the pandemia"
The dynamics of the pandemic depends on a fairly understandable value: how many people are infected on average, one infected while it is angry. If this value is larger than one, then we will have an exponential increase in incidence. If less than one is a decline. A decrease in the incidence is achieved by various methods: social distance, wearing masks, remote work, avoiding mass clusters of people, observing hygiene rules and immunization. Each measure and every person contributes.
8. "My acquaintance or acquaintance was vaccinated, but still fell ill"
Yes, this is possible. Especially if the acquaintance was vaccinated recently - or, conversely, was vaccinated more than a year ago and he had almost no antibodies. Most likely, the course of the disease without vaccination would be much worse.
9. "I will not get sick, I have a good immunity"
The phrase "good immunity" makes little sense. Until your body encounters a specific virus or vaccine from it, antibodies or cellular immunity from this virus will not appear. After vaccination or illness, your resistance to a specific pathogen will increase significantly, but will not change in relation to other pathogens.
I heard the opinion that the best protection against diseases is a healthy lifestyle. Healthy lifestyle is great! But the run of a cowardly, the Mediterranean diet and quality sleep will not provide you with cellular immunity or antibodies to coronavirus.
(An important point: eating dietary supplements, meditation and intestinal cleaning from toxins have nothing to do with a healthy lifestyle. No!)
Author: regional 10. “Sputnik V” Vaccine contains tris, and it is forbidden to introduce even animals! ”
Tris is a solution that is common in molecular biology, which plays the role of a buffer with physiological values of pH. It is used not only in the "satellite", but also, for example, in the Moderna vaccine. It is used in medicine in the treatment of metabolic acidosis (however, in much larger quantity than it is contained in vaccines). Most likely, rumors about the danger of Tris took up the signature to the technical tris, which is intended for use in laboratories. As, for example, there is a technical alcohol that is not sprinkled during feasts.
11. "I do not trust the" Putin vaccine. " Here I would swing the Western! "
It would be wonderful if Russia appeared in Russia from coronavirus from Pfizer, Moderna, Cansino Biologics, Astrazeneca and Johnson & Johnson. Alas, I cannot influence this. Nevertheless, the satellite vaccine was developed not by officials from the state, but by highly qualified specialists. The main creator of the vaccine is Denis Logunov - a respected and quoted scientist. In any falsifications, the developers of the vaccine were not previously seen. At the same time, the "satellite" is registered in almost 70 countries.
The principle of all approved vector and MRNO vaccines, including the “satellite” and the same Pfizer, is very similar: some human cells will produce a superficial SARS-COV-2 coronavirus and exhibit its parts to their surface. Then the cells of the immune system recognize areas of foreign protein and will begin to actively share. Some cells will produce antibodies against this protein, some will become memory cells and will be ready to fight a full virus in case of its appearance.
12. “This is not a vaccine, but genetic therapy! The vaccine genetically modifies me! "
The satellite vaccine can force some human cells (mainly muscle tissue at the injection site) to produce one of the coronavirus proteins. Adenoviruses do not specifically embed their genetic material in the chromosomes of the cells that they infect. Therefore, in the case of a vaccine, this cannot be expected. In any case, the most likely fate of cells producing coronavirus protein is subsequent death. This is not scary, because muscle cells die regularly, including during muscle loads. And they are easily restored.
If someone is afraid that the vector vaccine can genetically modify a person, he must understand that any virus that causes even the lightest cold makes our cells produce foreign proteins. In other words, real viruses “modify” us much more than a vaccine.
13. "The vaccine was made too fast"
The charm of vector and MRNA vaccines is that it is easy to replace the gene that they deliver in them. Therefore, as soon as the genetic sequences of the SARS-COV-2 coronavirus coronavirus were read and published, scientists from around the world could immediately begin work without even having a virus in the hands. Such vaccines are created on the basis of earlier developments for the delivery of genetic material. It is like a designer in which it is not difficult to change the details.
It is more difficult to conduct clinical trials and establish mass production. With the first, alas, the rate of spread of infection helps. It is not difficult to gain sufficient statistics of cases of infection. And the mass production of vaccines was established due to serious financial investments.
14. "You cannot be vaccinated during the epidemic"
Everything is exactly the opposite. What is an epidemic for an individual? This is an increased probability of getting sick. Therefore, it is especially important to vaccinate in the epidemic. If the epidemic suddenly ends, then the point of vaccination will be less, because the probability of getting an infection will not be so high. At the same time, the more people are vaccinated, the greater the likelihood that the epidemic will end and the fewer deaths and disabilities will be.
Do you want fewer victims? Please arrive a "companion".
15. "The vaccine may have unknown effects in the future"
It is unlikely that the long -term or short -term effects of the satellite vaccine will exceed those from the usual adenovirus infection. The spike-shaped protein that some human cells will produce will not be part of any viruses and will be disposed of the immune system.
At the same time, there are very real fears about unknown effects in the future from the most coronavirus infection. Many people have already encountered long -term smell loss and other post -shock symptoms. Coronavirus SARS-COV-2 penetrates the cells through receptors that are found not only in the cells of the pulmonary epithelium, but also in some intestinal parts, in the heart, kidneys, pancreas, as well as in male and female sexual tissues. So I would rather expect problems with the fertility from the Covid-19, not the vaccine.

16. "The third phase of clinical studies of the vaccine satellite V is not passed"
The Lancet magazine published intermediate data from the third phase of clinical studies of the vaccine on the sample of more than twenty thousand people. And although research can last a long time, this will not change the fact that vaccinated people in this study were much less common. Moreover, the results for the satellite vaccine are similar to the results for other similar vaccines produced in other countries. I decided to get used to the satellite vaccine before this publication, because earlier in The Lancet magazine there were impressive results on the effectiveness of the vector vaccine from the Cansino Biologics, very similar to the "satellite V".
17. "An article about the satellite in The Lancet contains errors and/or fabricated"
Indeed, the article about the "satellite" in The Lancet was criticized. But then the response of the authors was published there. When evidence of errors or forgery appears in an article in a scientific journal of this level, the article is usually called. For example, The Lancet magazine revoked an article whose authors unreasonably associated vaccinations against measles, rubella and pigs with the development of autism. An article about the satellite vaccine is not withdrawn. In addition, there are other articles about the effectiveness of this vaccine.
18. "I do not want to vaccinate every six months"
Indeed, studies show that immunity to coronaviral infection falls over time. And revaccination can significantly reduce the risk of infection against the background of two doses already available. What will happen next is unknown: science moves forward and, possibly, will offer new, even more effective vaccines and medicines. Perhaps the pandemic will end. But it must be experienced. And try to stay healthy.
19. “This is a personal matter for everyone. If you want, get rid of, and leave me alone "
Alas, this is not entirely true. To win the pandemia, we need to achieve population immunity. To make one person infect less than one person. This can only be achieved if mass vaccination is carried out or if most people get sick (which leads to mass deaths and disabled). For now, we can not vaccinate from the Covid-19, but I hope this will change in the future. Given the fact that the immunity to the Coronavirus SARS-COV-2 weakens over time, it is desirable that mass vaccination takes place in a short time. Refusing to vaccinate, you not only increase the risk of your own death, but also the death of relatives, friends and friends. And also delay the moment when we can forget about this pandemic as a terrible dream.
20. "Proponents of vaccines bought"
I cannot speak for everyone, but I will say for myself. I have never received money from the state or from vaccines manufacturers for such posts or lectures. Well, imagine how many people need to buy! According to vector and MRNA vaccines from SARS-COV-2, there are hundreds of scientific publications of various scientific groups from around the world. According to the satellite vaccine, there are data obtained not only in Russia, but also in Argentina, San Marino and other countries.
Conclusion
Over the day yesterday in Russia, Kovid took the lives of 1192 people. In my opinion, this is a tragedy. And I am sad to realize that many deaths could have been avoided if we were more willing and actively vaccinated from coronavirus. The vaccine will not make you barren, will not turn you into mutants, you will not grow your tail and the third ear. You will not only protect yourself - you will bring humanity closer to the step closer to the end of the pandemic.
I hope my text will convince someone to get used to or revaccinated from coronavirus. I would be glad if you send a post to those who still doubt whether to put a “satellite” or not.